F2100300

Anti-Mouse CD3ε, Functional Grade (Clone:145-2C11)功能抗体 (新品)

¥240.00 – ¥528.00

说明书

分子靶点：CD3E, CD3 epsilon, CD3ε
种属：小鼠 (Mouse)

亚型：Armenian Hamster IgG
克隆号：145-2C11

在售SKU, 70-AM003E-20, 70-AM003E-50, 70-AM003E-100, AM003E, 70-F2100300-25, 70-F2100300-100

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Size
库存号

描述

文章目录[隐藏]

分子信息
CD3E 分子靶点信息概述
CD3E 分子靶点综述
- 小鼠 Mouse Cd3e 分子靶点信息
- 小鼠 Mouse Cd3e 靶点分子功能（预测）

商品名	Anti-Mouse CD3ε, Functional Grade (Clone:145-2C11)功能抗体
靶点	CD3E, CD3 epsilon, CD3ε
亚型	Armenian Hamster IgG
克隆号	145-2C11
推荐应用	功能试验(T 细胞活化), FCM, IF, IHC, IP, WB
浓度	2 mg/mL
纯化	亲和层析
储存液	磷酸盐缓冲液(pH7.2)
保存条件	2 - 8℃，切勿冻存

分子信息

概述小鼠 CD3E, CD3 epsilon, CD3ε 靶点信息

CD3E 分子靶点信息概述

分子名：CD3E, CD3e molecule
基因家族：CD molecules
全称：CD3e antigen, epsilon polypeptide (TiT3 complex); CD3e molecule, epsilon (CD3-TCR complex)

CD3E 分子靶点综述

CD3也称为T3，是免疫球蛋白超家族的一员，在抗原识别、信号传导和T细胞活化中具有重要作用。CD3ε的分子量为20 kD，是CD3分子的亚基，后者由2个CD3ε、1个CD3γ、1个CD3δ和1个CD3ζ (CD247)构成，并与α/β或γ/δT细胞受体(TCR)形成异源二聚体。CD3表达于所有成熟T细胞、NKT细胞和部分胸腺细胞。

小鼠 Mouse Cd3e 分子靶点信息

分子名：Cd3e, CD3 antigen, epsilon polypeptide
别称：
- AI504783
- CD3
- CD3epsilon
- expressed sequence AI504783
- T3-epsilon chain
- T3e
基因序列：NCBI_Gene: 12501
蛋白序列：

小鼠 Mouse Cd3e 靶点分子功能（预测）

Predicted to enable several functions, including SH3 domain binding activity; identical protein binding activity; and protein heterodimerization activity. Involved in nervous system development and positive regulation of cell adhesion. Acts upstream of or within several processes, including positive regulation of T cell activation; positive regulation of cytokine production; and regulation of signal transduction. Located in several cellular components, including dendritic spine; external side of plasma membrane; and immunological synapse. Part of alpha-beta T cell receptor complex. Is expressed in colon and hemolymphoid system. Human ortholog(s) of this gene implicated in immunodeficiency 18. Orthologous to human CD3E (CD3e molecule).