Home-based exercise alters pulmonary function and cellular stress markers in overweight middle-aged men during covid-19 Home quarantine

Background This study aimed to investigate the effects of a combined home-based exercise program on potential indicators of severe coronavirus disease 2019 (COVID-19) in overweight middle-aged men during home quarantine caused by COVID-19. Methods Forty men (aged 45–64 years) were assigned to the exercise (EXE, n?=?20) or control (CON, n?=?20) groups. A 6-week combined program was carried out three days/week, starting at 20?min per session at 50% maximal heart rate (HRmax) and advancing to 45?min at 70% HRmax. Pulmonary functional and cellular stress biomarkers were measured before and after the training program. Analysis of the covariance (ANCOVA) was used for comparison between the two groups considering the baseline values. Results Thirty-six participants (EXE, n?=?17; CON, n?=?19) completed the research protocol. The EXE group showed post-training improvements in forced vital capacity (FVC), forced expiratory volume in 1?s (FEV1), FEV1/FVC, Vital capacity (VC), and Forced expiratory flow at 25-75% (FEF25-75) compared to the CON group (P?

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